Isotopically Labeled Compounds
Medchemexpress LLC Ezetimibe-d4-1 | 1093659-89-2 | MFCD08063570 | 99.3% | 413.45 | C24H17D4F2NO3 | 10 MG
Ezetimibe-d4-1 is a deuterium-labeled analogue of ezetimibe used as an analytical internal standard for quantitative mass spectrometry and method development. It provides a defined mass shift for accurate quantitation and is supplied with high reported purity suitable for bioanalytical applications.
- Deuterium-labeled internal standard for LC-MS/MS.
- High purity (99.3%) for reliable analytical results.
- Molecular weight 413.45 for precise mass calibration.
- Powder formulation with storage recommended at -20°C for long-term stability.
- Suitable for method validation and pharmacokinetic studies.
- Available in small pack sizes for laboratory use.
Cambridge Isotope Laboratories GLYCAN-O31-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
GLYCAN-O31-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
Medchemexpress LLC Cyclamic Acid-d11 | 1215770-73-2 | 99.9% | 1 MG
Cyclamic Acid-d11 is the deuterium labeled Cyclamic acid, a widely used artificial sweetener in food and pharmaceuticals. This product is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes like deuterium have been incorporated into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC L-valine-d8 | 35045-72-8 | MFCD00144704 | 99.8% | 125.20 g·mol⁻¹ | C5H3D8NO2 | 10 MG
L-Valine-d8 is the deuterated isotopologue of the essential amino acid L-valine, labeled with eight deuterium atoms and supplied for research use as a stable isotope standard or for labeled synthesis. It is commonly used as an internal standard in mass spectrometry and for metabolic and isotopic-labeling studies.
- Deuterated with eight deuterium atoms for mass-difference applications.
- High isotopic enrichment, suitable for quantitative MS analysis.
- High chemical purity for research applications.
- Available in small solid vials and solution formats for flexible use.
Medchemexpress LLC Pefloxacin-d5 (pefloxacinium-d5) | 1228182-51-1 | MFCD16652561 | 98.3% | 338.39 | C17H15D5FN3O3 | 10 MG
Pefloxacin-d5 is the deuterium-labeled analogue of the fluoroquinolone antibiotic pefloxacin, provided as a high-purity stable isotope standard for use as an internal standard in quantitative mass spectrometry, pharmacokinetic, and infection studies.
- High purity (98.3%).
- Chemical formula: C17H15D5FN3O3.
- Molecular weight: 338.39.
- CAS number: 1228182-51-1.
- Suitable for quantitative LC-MS/MS and pharmacokinetic studies.
- 10 mg packaging available.
Medchemexpress LLC D18 | 2230218-36-5 | 98.79% | C21H28N6 | 25 MG
D18 is an immune modulator and TLR7/8 dual agonist, enhancing PD-L1 expression via epigenetic regulation to increase tumor sensitivity to PD-1/PD-L1 blockade. It also serves as an ADC cytotoxin, exhibiting strong immune activation and anti-tumor activity, frequently used in cancer research, especially for colon cancer.
- Functions as a TLR7/8 dual agonist (EC50 = 24 nM for hTLR7, 10 nM for hTLR8).
- Increases tumor sensitivity to PD-1/PD-L1 blockade.
- Exhibits strong immune activation and anti-tumor activity.
- Frequently employed in cancer research, particularly for colon cancer.
- Elevates IFN-γ, TNF-α, IL-1β, IL-12 p40, and IP-10 in hPBMCs (in vitro).
- Inhibits tumor growth in BALB/c mice bearing CT26 tumors (in vivo).
- Increases immune cell penetration.
- Demonstrates good safety.
Medchemexpress LLC 1-hexadecanol-d5 | 1219799-18-4 | 99.2% | 10 MG
1-Hexadecanol-d5 is the deuterium-labeled analogue of 1-hexadecanol, provided as a high-purity stable isotope standard for analytical use. It is supplied as a white to off-white solid and is intended for use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS analyses.
- High purity: 99.20%.
- Molecular formula: C16H29D5O; molecular weight: 247.47.
- Available in small analytical pack sizes, including 10 mg.
- Soluble in DMSO; warming and sonication can improve dissolution.
- Suitable as a tracer and internal standard for quantitative analysis.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Appearance: white to off-white solid.
Cambridge Isotope Laboratories S-Adenosyl-L-Homocysteine (Adenosine-13C10) | 979-92-0 | MFCD00037388 | 0.1 mg
S-Adenosyl-L-Homocysteine (Adenosine-13C10) | Purity: 95% | Mol Wt: 394.34 | 979-92-0 | MFCD00037388 | 0.1 mg
Cambridge Isotope Laboratories ADIPIC ACID (3,3,4,4-D4, 98%), 0.5 G, 121311-78-2
ADIPIC ACID (3,3,4,4-D4, 98%), 0.5 G, 121311-78-2
Cambridge Isotope Laboratories CHOLESTEROL (2,2,3,4,4,6-D6, 97-98%), 0.1 G, 92543-08-3
CHOLESTEROL (2,2,3,4,4,6-D6, 97-98%), 0.1 G, 92543-08-3
Cambridge Isotope Laboratories PALMITIC ACID (13,13-D2, 98%), 0.5 G
PALMITIC ACID (13,13-D2, 98%), 0.5 G
Cambridge Isotope Laboratories DIETHYLAMINE (DIMETHYL-D6, 98%), 0.1 G
DIETHYLAMINE (DIMETHYL-D6, 98%), 0.1 G
Cambridge Isotope Laboratories L-TYROSINE (3,3-D2, 98%), 0.5 G, 72963-27-0
L-TYROSINE (3,3-D2, 98%), 0.5 G, 72963-27-0
Cambridge Isotope Laboratories PALMITIC ACID (7,7,8,8-D4, 98%), 0.5 G
PALMITIC ACID (7,7,8,8-D4, 98%), 0.5 G
Cambridge Isotope Laboratories PROPIONIC ACID (2,2-D2, 98%), 5 G, 19136-91-5
PROPIONIC ACID (2,2-D2, 98%), 5 G, 19136-91-5